Structural elucidation of Natural Products
Structural elucidation of Natural Products involves determining the precise chemical structure of compounds derived from natural sources. This process is crucial for understanding the bioactivity, functionality, and potential therapeutic applications of Natural Products. This process begins after a compound has been isolated and involves a combination of analytical techniques to uncover its detailed chemical structure. Key methods include nuclear magnetic resonance (NMR) spectroscopy, which provides information on the arrangement of atoms within the molecule, and mass spectrometry (MS), which offers insights into the molecular weight and fragmentation patterns of the compound. Infrared (IR) spectroscopy further assists by identifying functional groups based on their vibrational frequencies. X-ray crystallography can be used to determine the three-dimensional arrangement of atoms in a crystalline form of the compound.
3-1: Nuclear Magnetic Resonance
3-2: Mass Spectroscopy
3-3: X-Ray
3-4: Crystallography
3-5: Infrared Rays Spectroscopy